Anti-ANLN Polyclonal Antibody
品牌：solarbio | 货号：K008304P
| 英文名称 | Anti-ANLN Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | scra;Scraps |
| 应用 | IHC |
| 稀释比例 | IHC 1:25-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 124/120kDa |
| Gene ID | 54443 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ANLN |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ANLN |
| Subcellular Locations | Nucleus |
| Swiss Prot | Q9NQW6 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | ?Anillin, also known as scraps homolog, is an evolutionarily conserved Actin- binding protein required for cytokinesis that was first identified in Drosophila melanogaster. Anillin is a ubiquitously expressed protein with highest expression levels in the central nervous system. It is predominantly found in the nucleus and it localizes to the cleavage furrow during cytokinesis, forming a ring with the help of Rac GTPase. During cytokinesis, Anillin interacts with CD2AP and functions to concentrate Rho A and maintain the localization of active Myosin. In Anillin knockout cells the cleavage furrow fails to complete ingression. Anillin expression levels fluctuate with the cell cycle, peaking in mitosis.? |