Anti-CFL1 Polyclonal Antibody
品牌:solarbio | 货号:K106947P
英文名称 |
Anti-CFL1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
18 kDa phosphoprotein;CFL;CFL1;Cofilin 1;cofilin 1 (non muscle);Cofilin;non muscle isoform;p18 |
应用 |
WB IHC |
稀释比例 |
WB 1:10000-15000. IHC 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
19kDa |
Gene ID |
1072 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human CFL1 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human CFL1 |
Subcellular Locations |
All |
Swiss Prot |
P23528 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus. |