Anti-PNP Polyclonal Antibody
品牌:solarbio | 货号:K004206P
英文名称 |
Anti-PNP Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
NP;PRO1837;PUNP |
应用 |
WB IP |
稀释比例 |
WB 1:500-2000. IP 1:50-100. |
交叉反应 |
Human Mouse |
蛋白分子量 |
32kDa |
Gene ID |
4860 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human PNP |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human PNP |
Subcellular Locations |
Cytoplasm cytoskeleton |
Swiss Prot |
P00491 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2. |