Anti-IL3RA Polyclonal Antibody
品牌：solarbio | 货号：K003728P
| 英文名称 | Anti-IL3RA Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CD123;IL3R;IL3RAY;IL3RX;IL3RY;hIL-3Ra |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 43kDa |
| Gene ID | 3563 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human IL3RA |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human IL3RA |
| Subcellular Locations | Membrane Single-pass type I membrane protein |
| Swiss Prot | P26951 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. |