Anti-BMP4 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-BMP4 Polyclonal Antibody

品牌:solarbio | 货号:K106894P

英文名称 Anti-BMP4 Polyclonal Antibody
宿主 Rabbit
别名 BMP2B;BMP2B1;MCOPS6;OFC11;ZYME;bone morphogenetic protein 4
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:25-100.
交叉反应 Human
蛋白分子量 47kDa
Gene ID 652
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human BMP4
性状 液体
Public Immunogen Range A synthetic peptide of human BMP4
Subcellular Locations Cytoplasm
Swiss Prot P12644
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers.