Anti-BMP4 Polyclonal Antibody
品牌:solarbio | 货号:K106894P
英文名称 |
Anti-BMP4 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
BMP2B;BMP2B1;MCOPS6;OFC11;ZYME;bone morphogenetic protein 4 |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:25-100. |
交叉反应 |
Human |
蛋白分子量 |
47kDa |
Gene ID |
652 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human BMP4 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human BMP4 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
P12644 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. |