Anti-IRAK4 Polyclonal Antibody
品牌：solarbio | 货号：K106734P
| 英文名称 | Anti-IRAK4 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | IRAK-4;Renal carcinoma antigen NY-REN-64;Interleukin-1 receptor-associated kinase 4 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:25-100. |
| 交叉反应 | Human |
| 蛋白分子量 | 52kDa |
| Gene ID | 51135 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human IRAK4 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human IRAK4 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q9NWZ3 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation to form the Myddosome together with IRAK2. Phosphorylates initially IRAK1, thus stimulating the kinase activity and intensive autophosphorylation of IRAK1. |