Anti-IL17A Polyclonal Antibody
品牌:solarbio | 货号:K008040P
| 英文名称 | Anti-IL17A Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | IL17;CTLA8;IL-17;CTLA-8;IL-17A |
| 应用 | IHC |
| 稀释比例 | IHC 1:30-150. |
| 交叉反应 | Human |
| 蛋白分子量 | 18kDa |
| Gene ID | 3605 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human IL17A |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human IL17A |
| Subcellular Locations | Secreted |
| Swiss Prot | Q16552 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. |