Anti-APEH Polyclonal Antibody
品牌:solarbio | 货号:K004290P
英文名称 |
Anti-APEH Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
AARE;ACPH;APH;D3F15S2;D3S48E;DNF15S2;OPH |
应用 |
WB IP |
稀释比例 |
WB 1:500-2000. IP 1:20-50. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
81kDa |
Gene ID |
327 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human APEH |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human APEH |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
P13798 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma. |