Anti-MGEA5 Polyclonal Antibody
品牌：solarbio | 货号：K006754P
| 英文名称 | Anti-MGEA5 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | OGA;MEA5;NCOAT |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:25-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 103kDa |
| Gene ID | 10724 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human MGEA5 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human MGEA5 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | O60502 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT, which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications. Cleaves GlcNAc but not GalNAc from glycopeptides. Can use p-nitrophenyl-beta-GlcNAc as substrate but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc. Possesses hyaluronidase activity. Acetylates ‘Lys-8’ of histone H4 and ‘Lys-14’ of histone H3. Shows highest expression in the brain, placenta and pancreas. |