Anti-MCM3AP Polyclonal Antibody
品牌：solarbio | 货号：K007048P
| 英文名称 | Anti-MCM3AP Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | GANP;SAC3;MAP80 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 218kDa |
| Gene ID | 8888 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human MCM3AP |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human MCM3AP |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | O60318 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. This gene is expressed in the brain or in neuronal tissue. An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability.? |