Anti-Phospho-MAP3K7-S412 Polyclonal Antibody
品牌：solarbio | 货号：K006194P
| 英文名称 | Anti-Phospho-MAP3K7-S412 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CSCF;FMD2;MEKK7;TAK1;TGF1a |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human |
| 蛋白分子量 | 67kDa |
| Gene ID | 6885 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A phospho specific peptide corresponding to residues surrounding S412 of human MAP3K7 |
| 性状 | 液体 |
| Public Immunogen Range | A phospho specific peptide corresponding to residues surrounding S412 of human MAP3K7 |
| Subcellular Locations | Cell membrane Cytoplasm Cytoplasmic side Peripheral membrane protein |
| Swiss Prot | O43318 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. |