Anti-PFKFB2 Polyclonal Antibody
品牌：solarbio | 货号：K006024P
| 英文名称 | Anti-PFKFB2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | PFK-2/FBPase-2 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 58kDa |
| Gene ID | 5208 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PFKFB2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PFKFB2 |
| Subcellular Locations | Cytosol Nucleus |
| Swiss Prot | O60825 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. |