Anti-SQSTM1 Polyclonal Antibody
品牌:solarbio | 货号:K005444P
英文名称 |
Anti-SQSTM1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
A170;DMRV;FTDALS3;NADGP;OSIL;PDB3;ZIP3;p60;p62;p62B |
应用 |
WB IHC IF IP |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. IF 1:50-200. IP 1:50-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
48kDa |
Gene ID |
8878 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human SQSTM1 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human SQSTM1 |
Subcellular Locations |
Cytoplasm Cytoplasmic vesicle Endoplasmic reticulum Late endosome Lysosome Nucleus P-body autophagosome |
Swiss Prot |
Q13501 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. |