Anti-MMP14 Polyclonal Antibody
品牌：solarbio | 货号：K003409P
| 英文名称 | Anti-MMP14 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | MMP-14;MMP-X1;MT-MMP;MT-MMP 1;MT1-MMP;MT1MMP;MTMMP1;WNCHRS |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 66kDa |
| Gene ID | 4323 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human MMP14 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human MMP14 |
| Subcellular Locations | Cytoplasm Melanosome Membrane Single-pass type I membrane protein |
| Swiss Prot | P50281 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP’s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. |