Anti-CD74 Polyclonal Antibody
品牌：solarbio | 货号：K004121P
| 英文名称 | Anti-CD74 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | DHLAG;HLADG;II;Ia-GAMMA |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 34kDa |
| Gene ID | 972 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CD74 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CD74 |
| Subcellular Locations | Cell membrane Endoplasmic reticulum membrane Endosome Golgi apparatus Lysosome Single-pass type II membrane protein trans-Golgi network |
| Swiss Prot | P04233 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. |