Anti-ITGA2B Polyclonal Antibody
品牌：solarbio | 货号：K004131P
| 英文名称 | Anti-ITGA2B Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | BDPLT16;BDPLT2;CD41;CD41B;GP2B;GPIIb;GT;GTA;HPA3;PPP1R93 |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-2000. IF 1:10-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 113kDa |
| Gene ID | 3674 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ITGA2B |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ITGA2B |
| Subcellular Locations | Membrane Single-pass type I membrane protein |
| Swiss Prot | P08514 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. |