Anti-GRB2 Polyclonal Antibody
品牌:solarbio | 货号:K004140P
英文名称 |
Anti-GRB2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ASH;EGFRBP-GRB2;Grb3-3;MST084;MSTP084;NCKAP2 |
应用 |
WB IHC IF |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. IF 1:10-100. |
交叉反应 |
Human Mouse |
蛋白分子量 |
25kDa |
Gene ID |
2885 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human GRB2 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human GRB2 |
Subcellular Locations |
Cytoplasm Endosome Golgi apparatus Nucleus |
Swiss Prot |
P62993 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. |