Anti-MAP2K5 Polyclonal Antibody
品牌：solarbio | 货号：K004891P
| 英文名称 | Anti-MAP2K5 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | HsT17454;MAPKK5;MEK5;PRKMK5 |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 50kDa |
| Gene ID | 5607 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human MAP2K5 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human MAP2K5 |
| Subcellular Locations | Cytoskeleton Cytosol Nucleus |
| Swiss Prot | Q13163 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. |