Anti-Phospho-TNK2-Y284 Polyclonal Antibody
品牌：solarbio | 货号：K006246P
| 英文名称 | Anti-Phospho-TNK2-Y284 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ACK;ACK-1;ACK1;p21cdc42Hs |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human |
| 蛋白分子量 | 115kDa |
| Gene ID | 10188 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A phospho specific peptide corresponding to residues surrounding Y284 of human TNK2 |
| 性状 | 液体 |
| Public Immunogen Range | A phospho specific peptide corresponding to residues surrounding Y284 of human TNK2 |
| Subcellular Locations | Cell junction Cell membrane Cytoplasmic side Cytoplasmic vesicle Cytoplasmic vesicle membrane Endosome Membrane Nucleus Peripheral membrane protein adherens junction clathrin-coated pit clathrin-coated vesicle |
| Swiss Prot | Q07912 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. |