Anti-PC Polyclonal Antibody
品牌：solarbio | 货号：K004420P
| 英文名称 | Anti-PC Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | PCB |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-2000. IF 1:10-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 130kDa |
| Gene ID | 5091 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PC |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PC |
| Subcellular Locations | Mitochondrion matrix |
| Swiss Prot | P11498 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5′ UTRs, but encoding the same protein, have been found for this gene. |