Anti-TPP1 Polyclonal Antibody
品牌:solarbio | 货号:K004092P
英文名称 |
Anti-TPP1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CLN2;GIG1;LPIC;SCAR7;TPP-1 |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse |
蛋白分子量 |
61kDa |
Gene ID |
1200 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human TPP1 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human TPP1 |
Subcellular Locations |
Lysosome Melanosome |
Swiss Prot |
O14773 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. |