Anti-RAE1 Polyclonal Antibody
品牌：solarbio | 货号：K004734P
| 英文名称 | Anti-RAE1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | MIG14;MRNP41;Mnrp41;dJ481F12.3;dJ800J21.1 |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 41kDa |
| Gene ID | 8480 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human RAE1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human RAE1 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | P78406 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene. |