Anti-Delta4 Polyclonal Antibody
品牌:solarbio | 货号:K106504P
英文名称 |
Anti-Delta4 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
DLL4;AOS6;DLL 4;hdelta2;MGC126344 |
应用 |
WB |
稀释比例 |
WB 1:3000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
75kDa |
Gene ID |
54567 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human Delta4 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human Delta4 |
Subcellular Locations |
Cell membrane |
Swiss Prot |
Q9NR61 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The LIN-12/Notch family of transmembrane receptors is believed to play a central role in development by regulating cell fate decisions. Notch proteins have been found to be overexpressed or rearranged in human tumors. Ligands for Notch include Jagged, Jagged-2 and Delta. While blocking the differentiation of progenitor cells into the B-cell lineage, Delta promotes the emergence of a population of cells with T cell/NK-cell characteristics. The protein is a membrane protein expressed in heart, pancreas, brain and muscle during gastrulation and early organogenesis and in adult heart and lung. Delta-4 is a membrane protein that activates Notch-1 and Notch-4. It is expressed in a wide range of adult and fetal tissues, especially in vascular endothelium. |