Anti-IPO7 Polyclonal Antibody
品牌：solarbio | 货号：K007740P
| 英文名称 | Anti-IPO7 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | Imp7;RANBP7 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:100-300. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 120kDa |
| Gene ID | 10527 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human IPO7 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human IPO7 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | O95373 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran’s GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins. |