Anti-MYD88 Polyclonal Antibody
品牌:solarbio | 货号:K006796P
英文名称 |
Anti-MYD88 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
MYD88D |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:25-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
33kDa |
Gene ID |
4615 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human MYD88 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human MYD88 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
Q99836 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. |