Anti-Phospho-EGFR-T669 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-Phospho-EGFR-T669 Polyclonal Antibody

品牌:solarbio | 货号:K006171P

英文名称 Anti-Phospho-EGFR-T669 Polyclonal Antibody
宿主 Rabbit
别名 ERBB;ERBB1;HER1;NISBD2;PIG61;mENA
应用 WB IP
稀释比例 WB 1:500-2000. IP 1:50-100.
交叉反应 Human
蛋白分子量 134kDa
Gene ID 1956
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A phospho specific peptide corresponding to residues surrounding T669 of human EGFR
性状 液体
Public Immunogen Range A phospho specific peptide corresponding to residues surrounding T669 of human EGFR
Subcellular Locations Cell membrane Endoplasmic reticulum membrane Endosome Endosome membrane Golgi apparatus membrane Nucleus membrane Nucleus Secreted Single-pass type I membrane protein
Swiss Prot P00533
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.