Anti-HAVCR2 Polyclonal Antibody
品牌：solarbio | 货号：K003383P
| 英文名称 | Anti-HAVCR2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CD366;HAVcr-2;KIM-3;TIM3;TIMD-3;TIMD3;Tim-3 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-1000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 33kDa |
| Gene ID | 84868 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human HAVCR2 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human HAVCR2 |
| Subcellular Locations | Membrane Single-pass type I membrane protein |
| Swiss Prot | Q8TDQ0 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. |