Anti-AIFM3 Polyclonal Antibody
品牌：solarbio | 货号：K006947P
| 英文名称 | Anti-AIFM3 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | AIFL |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 67kDa |
| Gene ID | 150209 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human AIFM3 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human AIFM3 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q96NN9 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | AIFL (apoptosis-inducing factor-like), also known as AIFM3 (apoptosis-inducing factor, mitochondrion-associated, 3), is a 605 amino acid protein that localizes to the mitochondrion and contains one rieske domain. Expressed ubiquitously in tissues including liver, thymus, ovary, bone marrow and cerebral cortex, AIFL functions to induce apoptosis, specifically through a caspase-dependent pathway, and may also play a role in the modulation of mitochondrial membrane potential. Multiple isoforms of AIFL exist due to alternative splicing events. The gene encoding AIFL maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. |