Anti-CASP2 Polyclonal Antibody
品牌:solarbio | 货号:K004163P
英文名称 |
Anti-CASP2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CASP-2;ICH1;NEDD-2;NEDD2;PPP1R57 |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. |
交叉反应 |
Human Mouse |
蛋白分子量 |
51kDa |
Gene ID |
835 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human CASP2 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human CASP2 |
Subcellular Locations |
Cytosol Nucleus Mitochondrion |
Swiss Prot |
P42575 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer’s disease, Huntington’s disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |