Anti-SPOP Polyclonal Antibody
品牌：solarbio | 货号：K005350P
| 英文名称 | Anti-SPOP Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | AI315626;Pcif1;TEF2 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 42kDa |
| Gene ID | 20747 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of mouse SPOP |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of mouse SPOP |
| Subcellular Locations | Nucleus |
| Swiss Prot | Q6ZWS8 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. |