Anti-HNRNPL Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-HNRNPL Polyclonal Antibody

品牌:solarbio | 货号:K005832P

英文名称 Anti-HNRNPL Polyclonal Antibody
宿主 Rabbit
别名 HNRPL;P/OKcl.14;hnRNP-L
应用 WB IHC IF
稀释比例 WB 1:500-2000. IHC 1:50-100. IF 1:50-100.
交叉反应 Human Mouse Rat
蛋白分子量 64kDa
Gene ID 3191
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human HNRNPL
性状 液体
Public Immunogen Range Recombinant protein of human HNRNPL
Subcellular Locations Cytoplasm Nucleus nucleoplasm
Swiss Prot P14866
克隆类型 Polyclonal Antibody
背景资料 Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene.