Anti-GMFG Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-GMFG Polyclonal Antibody

品牌:solarbio | 货号:K006930P

英文名称 Anti-GMFG Polyclonal Antibody
宿主 Rabbit
别名 GMF-GAMMA
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 17kDa
Gene ID 9535
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human GMFG
性状 液体
Public Immunogen Range Recombinant protein of human GMFG
Subcellular Locations Cytoplasm
Swiss Prot O60234
克隆类型 Polyclonal Antibody
背景资料 Glia maturation factor, gamma, also known as GMFG, is a 142 amino acid protein that belongs to the GMF subfamily of the larger actin-binding protein ADF family. GMF-gamma is expressed predominantly in lung, heart and placenta. GMF-gamma is considered a candidate regulatory growth factor protein, mediating both paracrine and autocrine cell-cell interactions. GMF-gamma is phosphorylated at N-terminal serine, and its phosphorylation is enhanced by coexpression of dominant active Rac 1 and Cdc42. GMF-gamma expression is significantly increased in a cardiac ischemia/reperfusion model where inflammation and angiogenesis take place actively. As a regulator of actin-based cellular functions, GMF-gamma may provide a novel approach to modulate the pathophysiology of cardiovascular diseases. GMF-gamma is primarily found in proliferative and differentiative organs.