Anti-LDB3 Polyclonal Antibody
品牌：solarbio | 货号：K005264P
| 英文名称 | Anti-LDB3 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CMD1C;CMH24;CMPD3;CYPHER;LDB3Z1;LDB3Z4;LVNC3;MFM4;ORACLE;PDLIM6;ZASP |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 77kDa |
| Gene ID | 11155 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human LDB3 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human LDB3 |
| Subcellular Locations | Cell projection Cytoplasm Z line cytoskeleton myofibril perinuclear region pseudopodium sarcomere |
| Swiss Prot | O75112 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified; all isoforms have N-terminal PDZ domains while only longer isoforms (1, 2 and 5) have C-terminal LIM domains. |