Anti-P4HB Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-P4HB Polyclonal Antibody

品牌:solarbio | 货号:K106924P

英文名称 Anti-P4HB Polyclonal Antibody
宿主 Rabbit
别名 PDI;ERBA2L;PDI;PDIA1;PO4DB
应用 WB IHC
稀释比例 WB 1:8000-12000. IHC 1:50-200.
交叉反应 Human Mouse
蛋白分子量 57kDa
Gene ID 64714
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human P4HB
性状 液体
Public Immunogen Range A synthetic peptide of human P4HB
Subcellular Locations Cytoplasm
Swiss Prot P07237
克隆类型 Polyclonal Antibody
背景资料 This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis. Also acts a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP.