Anti-CDK6 Polyclonal Antibody
品牌：solarbio | 货号：K106911P
| 英文名称 | Anti-CDK6 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CDKN6;Cyclin-dependent kinase 6;Cell division protein kinase 6 |
| 应用 | WB |
| 稀释比例 | WB 1:5000-8000. |
| 交叉反应 | Human |
| 蛋白分子量 | 37kDa |
| Gene ID | 1021 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human CDK6 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human CDK6 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q00534 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Serine/threonine-protein kinase involved in the control of the cell cycle and differentiation;promotes G1/S transition. Phosphorylates pRB/RB1 and NPM1. Interacts with D-type G1 cyclins during interphase at G1 to form a pRB/RB1 kinase and controls the entrance into the cell cycle. Involved in initiation and maintenance of cell cycle exit during cell differentiation;prevents cell proliferation and regulates negatively cell differentiation, but is required for the proliferation of specific cell types (e.g. erythroid and hematopoietic cells). Essential for cell proliferation within the dentate gyrus of the hippocampus and the subventricular zone of the lateral ventricles.? |