Anti-GM2A Polyclonal Antibody
品牌:solarbio | 货号:K007248P
英文名称 |
Anti-GM2A Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
SAP-3;GM2-AP |
应用 |
WB IHC |
稀释比例 |
WB 1:200-1000. IHC 1:25-100. |
交叉反应 |
Human Mouse |
蛋白分子量 |
21kDa |
Gene ID |
2760 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human GM2A |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human GM2A |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
P17900 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants. |