Anti-VSIG8 Polyclonal Antibody
品牌：solarbio | 货号：K007223P
| 英文名称 | Anti-VSIG8 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-300. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 44kDa |
| Gene ID | |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human VSIG8 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human VSIG8 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q5VU13 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | VSIG8 (V-set and immunoglobulin domain-containing protein 8), also known as C1orf204, is a 414 amino acid single-pass type I membrane protein that contains two Ig-like V-type (immunoglobulin-like) domains. VSIG8 exists as two alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 1q23.2. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. The rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. |