Anti-GLDC Polyclonal Antibody
品牌:solarbio | 货号:K006116P
英文名称 |
Anti-GLDC Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
GCE;GCSP;HYGN1 |
应用 |
WB IHC |
稀释比例 |
WB 1:200-500. IHC 1:50-100. |
交叉反应 |
Human Mouse |
蛋白分子量 |
113kDa |
Gene ID |
2731 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human GLDC |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human GLDC |
Subcellular Locations |
Mitochondrion |
Swiss Prot |
P23378 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). |