Anti-ARHGDIB Polyclonal Antibody
品牌:solarbio | 货号:K003691P
英文名称 |
Anti-ARHGDIB Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
D4;GDIA2;GDID4;LYGDI;Ly-GDI;RAP1GN1;RhoGDI2 |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse |
蛋白分子量 |
23kDa |
Gene ID |
397 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human ARHGDIB |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human ARHGDIB |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
P52566 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]). |