Anti-ARHGDIB Polyclonal Antibody
品牌:solarbio | 货号:K003691P
| 英文名称 | Anti-ARHGDIB Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | D4;GDIA2;GDID4;LYGDI;Ly-GDI;RAP1GN1;RhoGDI2 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 23kDa |
| Gene ID | 397 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ARHGDIB |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ARHGDIB |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P52566 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]). |