Anti-PSMD3 Polyclonal Antibody
品牌:solarbio | 货号:K003488P
英文名称 |
Anti-PSMD3 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
P58;RPN3;S3;TSTA2 |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
61kDa |
Gene ID |
5709 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human PSMD3 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human PSMD3 |
Subcellular Locations |
Cytosol Nucleus secreted |
Swiss Prot |
O43242 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S3 family that functions as one of the non-ATPase subunits of the 19S regulator lid. Single nucleotide polymorphisms in this gene are associated with neutrophil count. |