Anti-PSMD3 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-PSMD3 Polyclonal Antibody

品牌:solarbio | 货号:K003488P

英文名称 Anti-PSMD3 Polyclonal Antibody
宿主 Rabbit
别名 P58;RPN3;S3;TSTA2
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 61kDa
Gene ID 5709
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human PSMD3
性状 液体
Public Immunogen Range A synthetic peptide of human PSMD3
Subcellular Locations Cytosol Nucleus secreted
Swiss Prot O43242
克隆类型 Polyclonal Antibody
背景资料 The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S3 family that functions as one of the non-ATPase subunits of the 19S regulator lid. Single nucleotide polymorphisms in this gene are associated with neutrophil count.