Anti-HNMT Polyclonal Antibody
品牌：solarbio | 货号：K003386P
| 英文名称 | Anti-HNMT Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | HMT;HNMT-S1;HNMT-S2;MRT51 |
| 应用 | WB IHC IF IP |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-100. IP 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 33kDa |
| Gene ID | 3176 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human HNMT |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human HNMT |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P50135 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. |