Anti-ESR2 Polyclonal Antibody
品牌:solarbio | 货号:K003406P
英文名称 |
Anti-ESR2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ER-BETA;ESR-BETA;ESRB;ESTRB;Erb;NR3A2 |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
59kDa |
Gene ID |
2100 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human ESR2 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human ESR2 |
Subcellular Locations |
Nucleus |
Swiss Prot |
Q92731 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. |