Anti-NKX2-1 Polyclonal Antibody
品牌:solarbio | 货号:K007566P
英文名称 |
Anti-NKX2-1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
BCH;BHC;NK-2;TEBP;TTF1;NKX2A;TITF1;TTF-1;NKX2.1 |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
42kDa |
Gene ID |
7080 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human NKX2-1 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human NKX2-1 |
Swiss Prot |
P43699 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias ‘TFF1’ with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. |