Anti-FKBP3 Polyclonal Antibody
品牌:solarbio | 货号:K004857P
英文名称 |
Anti-FKBP3 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
FKBP-25;FKBP-3;FKBP25;PPIase |
应用 |
WB IF IP |
稀释比例 |
WB 1:500-2000. IF 1:50-100. IP 1:50-100. |
交叉反应 |
Human |
蛋白分子量 |
25kDa |
Gene ID |
2287 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human FKBP3 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human FKBP3 |
Subcellular Locations |
Nucleus |
Swiss Prot |
Q00688 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin. |