Anti-FKBP3 Polyclonal Antibody
品牌:solarbio | 货号:K004857P
| 英文名称 | Anti-FKBP3 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | FKBP-25;FKBP-3;FKBP25;PPIase |
| 应用 | WB IF IP |
| 稀释比例 | WB 1:500-2000. IF 1:50-100. IP 1:50-100. |
| 交叉反应 | Human |
| 蛋白分子量 | 25kDa |
| Gene ID | 2287 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human FKBP3 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human FKBP3 |
| Subcellular Locations | Nucleus |
| Swiss Prot | Q00688 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin. |