Anti-KIAA0391 Polyclonal Antibody
品牌:solarbio | 货号:K006330P
英文名称 |
Anti-KIAA0391 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
MRPP3;PRORP |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Rat |
蛋白分子量 |
67kDa |
Gene ID |
9692 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human KIAA0391 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human KIAA0391 |
Subcellular Locations |
Mitochondrion |
Swiss Prot |
O15091 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer’s disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder -antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein BCL3 in the (14;19) translocations found in a variety of B cell malignancies. |