Anti-NEU1 Polyclonal Antibody
品牌：solarbio | 货号：K004418P
| 英文名称 | Anti-NEU1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | NANH;NEU;SIAL1 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 45kDa |
| Gene ID | 4758 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human NEU1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human NEU1 |
| Subcellular Locations | Lysosome Plasma membrane |
| Swiss Prot | Q99519 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as ‘protective protein’). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity. |