Anti-NTRK3 Polyclonal Antibody
品牌：solarbio | 货号：K004248P
| 英文名称 | Anti-NTRK3 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | GP145-TrkC;TRKC;gp145(trkC) |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 94kDa |
| Gene ID | 4916 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human NTRK3 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human NTRK3 |
| Subcellular Locations | Membrane Single-pass type I membrane protein |
| Swiss Prot | Q16288 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. |