Anti-IGF1R Polyclonal Antibody
品牌:solarbio | 货号:K106546P
英文名称 |
Anti-IGF1R Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CD221;IGFIR;IGFR;JTK13 |
应用 |
WB |
稀释比例 |
WB 1:3000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
67/114kDa |
Gene ID |
3480 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human IGF1R |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human IGF1R |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
P08069 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. |