Anti-IGF1R Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-IGF1R Polyclonal Antibody

品牌:solarbio | 货号:K106546P

英文名称 Anti-IGF1R Polyclonal Antibody
宿主 Rabbit
别名 CD221;IGFIR;IGFR;JTK13
应用 WB
稀释比例 WB 1:3000.
交叉反应 Human Mouse Rat
蛋白分子量 67/114kDa
Gene ID 3480
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human IGF1R
性状 液体
Public Immunogen Range A synthetic peptide of human IGF1R
Subcellular Locations Cytoplasm
Swiss Prot P08069
克隆类型 Polyclonal Antibody
背景资料 This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.