Anti-CCND3 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CCND3 Polyclonal Antibody

品牌:solarbio | 货号:K007414P

英文名称 Anti-CCND3 Polyclonal Antibody
宿主 Rabbit
别名 cyclin-D3
应用 IHC
稀释比例 IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 33kDa
Gene ID 896
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human CCND3
性状 液体
Public Immunogen Range A synthetic peptide of human CCND3
Subcellular Locations Cytoplasm Nucleus
Swiss Prot P30281
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb.