Anti-NODAL Polyclonal Antibody
品牌：solarbio | 货号：K006111P
| 英文名称 | Anti-NODAL Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | HTX5 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Rat |
| 蛋白分子量 | 40kDa |
| Gene ID | 4838 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human NODAL |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human NODAL |
| Subcellular Locations | Secreted |
| Swiss Prot | Q96S42 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which regulates early embryonic development. This protein is required for maintenance of human embryonic stem cell pluripotency and may play a role in human placental development. Mutations in this gene are associated with heterotaxy, a condition characterized by random orientation of visceral organs with respect to the left-right axis. |